Mitral Valve Prolapse Syndrome and Arrhythmias

The retrospective study included 64 patients, 26 men and 36 women, 25 to 50 years of age. Patients were monitored at the Lukavac Health Center Cardiology outpatient department from January 2007 to December 2009 and were subdivided into three groups. First group included patients who had subjective symptoms and had MVP and rarely arrhythmias, in the second and third group were patients who had subjective symptoms and clear clinical and diagnostic findings that indicate the MVP and arrhythmias. We took patients anamnesis, completed a clinical examination, electrocardiography, ergometry, Holter monitoring, Doppler echocardiography, LP, QTd and HRV. Using statistical methods we found that a group of risk factors obtained by a combination of direct and indirect noninvasive methods best predicts the emergence of complex arrhythmias, with a sensitivity of 92%. We also found that a group of risk factors obtained only by direct methods has a high value in forecasting the occurrence of complex arrhythmias in patients with MVP with a sensitivity of 88.3 %. We have not demonstrated the ability to predict the type of arrhythmic disorder. There is a significant direct correlation between the risk factors and the clinical, morphologic and hemodynamic features of mitral complex. All given results can help in clinical assessment and identifying high-risk group of patients with MVP for the occurrence of complex ventricular arrhythmias and sudden cardiac death.