• Title of article

    Gold(III) porphyrins as a new class of anticancer drugs: cytotoxicity, DNA binding and induction of apoptosis in human cervix epitheloid cancer cells

  • Author/Authors

    Zhu، Nianyong نويسنده , , Yu، Wing-Yiu نويسنده , , Che، Chi-Ming نويسنده , , Sun، Hongzhe نويسنده , , Sun، Raymond Wai-Yin نويسنده , , Ko، Chi-Bun نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2003
  • Pages
    -1717
  • From page
    1718
  • To page
    0
  • Abstract
    A series of gold(III) tetraarylporphyrins are stable in the presence of glutathione and exert much higher potency than cisplatin in killing human cancer cells, including the drug-resistant variants; the gold-induced cytotoxicity occurs through an apoptotic pathway according to laser confocal microscopy and flow cytometric studies.
  • Keywords
    inhibition of S(IV) autoxidation , isoprene , Sulphur dioxide , atmospheric VOC , isoprene oxidation
  • Journal title
    CHEMICAL COMMUNICATIONS - LETCHWORTH
  • Serial Year
    2003
  • Journal title
    CHEMICAL COMMUNICATIONS - LETCHWORTH
  • Record number

    70527