• Title of article

    Asymmetric Synthesis of the Main Pyridine Skeleton for a Macrobicyclic Antibiotic, Cyclothiazomycin

  • Author/Authors

    Yonezawa، Yasuchika نويسنده , , Shin، Chung-gi نويسنده , , Endoh، Nobuaki نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2003
  • Pages
    -642
  • From page
    643
  • To page
    0
  • Abstract
    Stoichiometric asymmetric reduction of the ketone group of a 2-acetyl-3,6-disubstituted pyridine derivative with an oxazaborolidine and N-ethyl-N-isopropyl anilineborane complex gave the corresponding (S)-lactone derivative 5 in 96% ee almost quantitatively. Hydrogenolytic cleavage of 5 gave the expected (S)-2-(1hydroxyethyl)pyridine derivative
  • Journal title
    BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN
  • Serial Year
    2003
  • Journal title
    BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN
  • Record number

    71487

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=71487