Title of article
On Reducing the Statespace of Hidden Markov Models for the Identity by Descent Process
Author/Authors
Sharon Browning، نويسنده , , Brian L. Browning، نويسنده ,
Issue Information
دوماهنامه با شماره پیاپی سال 2002
Pages
8
From page
1
To page
8
Abstract
Important methods for calculating likelihoods of genealogical relationships and mapping genes are based on hidden Markov models for the process of identity by descent along chromosomes. The computational time for the algorithms depends critically on the size of the statespace of the hidden Markov model. We describe the maximal grouping together of states of the model to reduce the size of the statespace. This grouping is based on pedigree symmetries. We also present an efficient algorithm for finding the maximal grouping
Keywords
identity by descent , Hidden Markov models , relationship inference , Genetic linkage analysis
Journal title
Theoretical Population Biology
Serial Year
2002
Journal title
Theoretical Population Biology
Record number
773672
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