• Title of article

    On Reducing the Statespace of Hidden Markov Models for the Identity by Descent Process

  • Author/Authors

    Sharon Browning، نويسنده , , Brian L. Browning، نويسنده ,

  • Issue Information
    دوماهنامه با شماره پیاپی سال 2002
  • Pages
    8
  • From page
    1
  • To page
    8
  • Abstract
    Important methods for calculating likelihoods of genealogical relationships and mapping genes are based on hidden Markov models for the process of identity by descent along chromosomes. The computational time for the algorithms depends critically on the size of the statespace of the hidden Markov model. We describe the maximal grouping together of states of the model to reduce the size of the statespace. This grouping is based on pedigree symmetries. We also present an efficient algorithm for finding the maximal grouping
  • Keywords
    identity by descent , Hidden Markov models , relationship inference , Genetic linkage analysis
  • Journal title
    Theoretical Population Biology
  • Serial Year
    2002
  • Journal title
    Theoretical Population Biology
  • Record number

    773672