Title of article
Genetic variations of the Plasmodium vivax dihydropteroate synthase gene
Author/Authors
Michela Menegon، نويسنده , , Giancarlo Majori، نويسنده , , Carlo Severini، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
4
From page
196
To page
199
Abstract
Dihydropteroate synthase gene of Plasmodium vivax was recently identified. In the present study, the sequences of the dyhydropteroate synthase gene of 68 P. vivax isolates from various geographic areas were compared. Sequencing revealed limited polymorphism at codons 383 and 553 in all analyzed samples. Interstrain analysis showed several genotypic variations in the tandem repeats domain which produce length polymorphism between different parasite isolates.
Keywords
malaria , Plasmodium vivax , Dihydropteroate synthase , polymorphism , Point mutations
Journal title
Acta Tropica
Serial Year
2006
Journal title
Acta Tropica
Record number
778362
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