Title of article
The in vitro effects of three lysosomotropic detergents against three human tumor cell lines
Author/Authors
Gene M. Dubowchik، نويسنده , , Susan L. Gawlak، نويسنده , , Raymond A. Firestone، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1995
Pages
6
From page
893
To page
898
Abstract
Three lysosomotropic detergents, N-dodecylimidazole (NDI) 1, and two new analogues, serine dodecylamide (SDA) 2 and O-methyl serine dodecylamide (MSD) 3, were tested against three human tumor cell lines in vitro: HCT116, RCA and MCF-7. All three demonstrated dose-related cytotoxicity which, except for a few cases, was also dependent on incubation time, and visually resembled cell death by apoptosis.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1995
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787438
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