Title of article
RES-701-1, comparative study of the synthetic and the microbial-origin compounds
Author/Authors
Ritusko Katahira، نويسنده , , Kenji Shibata، نويسنده , , Motoo Yamasaki، نويسنده , , YUZURU MATSUDA، نويسنده , , Mayumi Yoshida، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1995
Pages
6
From page
1595
To page
1600
Abstract
RES-701-1 is an ETB receptor selective antagonist obtained from Streptmyces sp. (IC50 = 10 nM). The chemically synthesized RES-701-1 which exhibits only micromolar affinity for ETB receptor was examined by 1H NMR and FAB-MS. The results indicated that the primary structures of the synthetic and the authentic RES-701-1 are identical but the 3D structure is completely different between them.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1995
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787567
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