• Title of article

    Inactivation of carboxypeptidase a by 2-benzyl-3,4-epithiobutanoic acid

  • Author/Authors

    Dong H. Kim and Seiichi Shin ، نويسنده , , Sang J. Chung، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1995
  • Pages
    6
  • From page
    1667
  • To page
    1672
  • Abstract
    2-Benzyl-3,4-epithiobutanoic acid was designed and synthesized as a pseudomechanism-based inactivator for carboxypeptidase A. Designing rationale, synthesis of racemic 2-benzyl-3,4-epithiobutanoic acid having (2S,3S)- and (2R,3R)-configurations, and inhibitory kinetic parameters and their implications are reported.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1995
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    787581