Title of article
5,6,7,8-Tetrahydroquinolones as antagonists at the glycine site of the NMDA receptor
Author/Authors
Michael Rowley، نويسنده , , Paul Leeson، نويسنده , , Sarah Grimwood، نويسنده , , George Marshall، نويسنده , , Kay Saywell، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1995
Pages
4
From page
2089
To page
2092
Abstract
The effect of reducing the benzo ring of a series of 4-hydroxyquinolone Glycine/NMDA antagonists is described. It is important that the ring be present, but not that it is aromatic. Provided that the correct lipophilic interactions are present, high affinity is found in 4-hydroxy-5,6,7,8-tetrahydroquinolones.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1995
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787658
Link To Document