Title of article
Synthetic inhibitors of interleukin-6 I: 2,3,7,8-tetrahydro-4-aryl-1H-cyclopent [e] imidazo [1,2-a]- pyridin-5(6H)-one and related compounds
Author/Authors
Jayaram R. Tagat، نويسنده , , Dennis V. Nazareno، نويسنده , , Stuart W. McCombie، نويسنده , , Beverly E. Barton، نويسنده , , Jennifer Shortall، نويسنده , , James Jackson، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1995
Pages
4
From page
2139
To page
2142
Abstract
A versatile synthetic route to the title class of compounds and the development of an orally absorbed analogue of the lead structure are described. The minimum structural requirements needed in the compounds related to 1 for the inhibition of interleukin-6 were identified.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1995
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787669
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