Title of article
Ring size effect in the PKC inhibitory activities of perhydroazepine analogs of balanol
Author/Authors
Yen-Shi Lai*، نويسنده , , David S. Menaldino، نويسنده , , Jeffrey B. Nichols، نويسنده , , G. Erik Jagdmann Jr.، نويسنده , , Frankie Mylott، نويسنده , , Jan Gillespie، نويسنده , , Steven E. Hall، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1995
Pages
4
From page
2151
To page
2154
Abstract
Analogs 3–5 of balanol (−)-1, a potent protein kinase C (PKC) inhibitor, were synthesized with the perhydroazepine moiety replaced by a smaller ring. Their in vitro inhibitory activities against PKC revealed a significant relationship between ring size and potency.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1995
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787672
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