Title of article
Synthesis and in vitro biological evaluation of new triphenylethylene platinum (II) complexes
Author/Authors
Yuehua He، نويسنده , , Serge Groleau، نويسنده , , RenéC. -Gaudreault، نويسنده , , Madeleine Caron، نويسنده , , Hélène-M. Thérien، نويسنده , , Gervais Bérubé، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1995
Pages
6
From page
2217
To page
2222
Abstract
In our search for a chemotherapeutic agent with a better therapeutic index and selectivity for the treatment of breast cancer, we have synthesized cytotoxic triphenylethylene derivatives. The synthesis of this type of compound is straightforward and efficient. The biological activity of these compounds was evaluated in vitro on ER+ and ER- human breast tumor cell lines: MCF-7 and MDA-MB-231.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1995
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787684
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