• Title of article

    Synthesis of novel iodinated radioligands with high affinity and selectivity for CCK-B/gastrin receptors

  • Author/Authors

    D. C. Horwell، نويسنده , , J. C. Hunter-Cevera، نويسنده , , C. O. Kneen، نويسنده , , M. C. Pritchard، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1995
  • Pages
    6
  • From page
    2501
  • To page
    2506
  • Abstract
    The syntheses of two non-peptide radio-iodinated ligands [125I]-PD142308 and [125I]-PD142251 with high affinity and selectivity for the CCK-B/gastrin receptor are described via a route which introduces the radiolabel at the final or penultimate step. The CCK-A and CCK-B binding affinities of both ligands are described.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1995
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    787735