Title of article
Synthesis of conformationally-constrained stereospecific analogs of glutamic acid as antagonists of metabotropic receptors
Author/Authors
Frédérique Tellier، نويسنده , , Francine Acher، نويسنده , , Isabelle Brabet، نويسنده , , Jean-Philippe Pin، نويسنده , , Joël Bockaert، نويسنده , , Robert Azerad، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1995
Pages
6
From page
2627
To page
2632
Abstract
Rigid analogs of ACPD have been synthesized to mimick different potential conformations of ACPD in aqueous solution. One of them, (±)-ABHD-I is a competitive antagonist at mGluR1a receptor with a KB value of 300 μM.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1995
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787757
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