Title of article
Amino acid-derived piperidides as novel CCKB ligands with anxiolytic-like properties
Author/Authors
Mark W. Holladay، نويسنده , , Michael J. Bennett، نويسنده , , Hao Bai، نويسنده , , Jeffrey W. Ralston، نويسنده , , James F. Kerwin Jr.، نويسنده , , Michael Stashko، نويسنده , , Thomas R. Miller، نويسنده , , Alyssa B. OʹNeill، نويسنده , , Alex M. Nadzan، نويسنده , , Jorge Brioni، نويسنده , , Chun Wel Lin، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1995
Pages
6
From page
3057
To page
3062
Abstract
The development of a novel series of carbamoylamino acid benzoylpiperidides as CCKB ligands is described. Selected members of the series antagonized CCK8-induced calcium mobilization and showed efficacy in the mouse elevated-plus maze, a measure of potential anxiolytic activity.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1995
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787836
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