• Title of article

    Synthesis and biological activity of a series of 4-aryl substituted benz[b]azepines: Antagonists at the strychnine-insensitive glycine site

  • Author/Authors

    Paul F. Jackson، نويسنده , , Timothy W. Davenport، نويسنده , , Laura Garcia، نويسنده , , Jeffrey A. McKinney، نويسنده , , Margaret G. Melville، نويسنده , , Gregory G. Harris، نويسنده , , Marc J. Chapdelaine، نويسنده , , James R. Damewood، نويسنده , , Linda M. Pullan، نويسنده , , Jeffrey M. Goldstein، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1995
  • Pages
    4
  • From page
    3097
  • To page
    3100
  • Abstract
    A series of 4-arylbenz[b]azepine analogs were prepared and shown to act as antagonists at the strychnine-insensitive glycine receptor. The heteroaryl substituted benz[b]azepine derivative 11 also showed excellent in vivo activity.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1995
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    787843