Title of article
New reagents for controlled release of nitric oxide. Structure-stability relationships
Author/Authors
Masayuki Kato، نويسنده , , Shigetaka Nishino، نويسنده , , Mitsuko Ohno، نويسنده , , Shinichi Fukuyama، نويسنده , , Yasuhiro Kita، نويسنده , , Yoshimi Hirasawa، نويسنده , , Isao Nakanishi، نويسنده , , Hisashi Takasugi، نويسنده , , Kazuo Sakane، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
6
From page
33
To page
38
Abstract
The synthesis and structure-stability relationships of a series of novel FK409 derivatives (1, 2, and 3) are described. The rates of decomposition in aqueous solution (pH 8.0, 30 °C) were parallel with those of spontaneous NO release measured by ESR spectroscopy using carboxy-PTIO. The compounds can cover a wide range of NO releasing rates by appropriate modification of the molecule.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787851
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