Title of article
Preparation, characterization and DNA photocleavage of diazapyrene-tethered oligothymidylates
Author/Authors
Hisafumi Ikeda، نويسنده , , Kaoru Fuji، نويسنده , , Kiyoshi Tanaka، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
4
From page
101
To page
104
Abstract
Several diazapyrene-tagged oligodeoxynucleotides were synthesized and characterized. The interaction of these modified oligomers with complementary strands indicated that introduction of the diazapyrene moiety increased the stability of the duplex as compared to that of native oligomers. DNA cleavage experiments with diazapyrene-tagged oligomers induced localized scission at the duplex region.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787865
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