Title of article
Phosphonic acid and phosphinic acid tripeptides as inhibitors of glutathionylspermidine synthetase
Author/Authors
Christophe Verbruggen، نويسنده , , Sofie De Craecker، نويسنده , , Padinchare Rajan، نويسنده , , Xian-Yun Jiao، نويسنده , , Marianne Borloo، نويسنده , , Keith Smith، نويسنده , , Alan H. Fairlamb، نويسنده , , Achiel Haemers، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
6
From page
253
To page
258
Abstract
A series of phosphonic and phosphinic acid derivatives of glutathione were synthesized as potential inhibitors of glutathionylspermidine synthetase, an essential enzyme in the biosynthesis of trypanothione in trypanosomatids. The compounds showed moderate activity.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787895
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