• Title of article

    Polyanion inhibitors of human immunodeficiency virus. Part IV. - polymerized anionic surfactants: Influence of the density and distribution of anionic groups on the antiviral activity

  • Author/Authors

    Alain Leydet، نويسنده , , Philippe Barthélémy، نويسنده , , Bernard Boyer ، نويسنده , , Gérard Lamaty، نويسنده , , Jean-Pierre Roque، نويسنده , , Myriam Witvrouw، نويسنده , , Erik De Clercq، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1996
  • Pages
    6
  • From page
    397
  • To page
    402
  • Abstract
    The synthesis of a series of new polyamions, via γ-polymerization, of ω-unsaturated multi-charged anionic surfactants, has been realized. These polyanions were evaluated for their activity against HIV-1. All tested compounds proved active without presenting toxicity to the host cells (CEM-4 or MT-4).
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1996
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    787925