• Title of article

    Anti-HIV activity of quassinoids

  • Author/Authors

    Masayoshi Okano، نويسنده , , Narihiko Fukamiya، نويسنده , , Kiyoshi Tagahara، نويسنده , , L. Mark Cosentino، نويسنده , , Thomas Tung-Ying Lee، نويسنده , , Susan Morris-Natschke، نويسنده , , Kuo-Hsiung Lee، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1996
  • Pages
    6
  • From page
    701
  • To page
    706
  • Abstract
    Eighteen quassinoid glycosides and nine known quassinoids were tested for inhibitory activity against HIV replication in H9 lymphocytic cells. Of the compounds tested, shinjulactone C (20) demonstrated the highest anti-HIV activity (EC50 = 10.6 μM) in the absence of cytotoxicity with a therapeutic index of>25.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1996
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    787984

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=787984