Title of article
A novel class of antagonists for metabotropic glutamate receptors, 7-(Hydroxyimino)cyclopropa[b]chromen-1a-carboxylates
Author/Authors
Hirokazu Annoura، نويسنده , , Atsuko Fukunaga، نويسنده , , Mayumi Uesugi، نويسنده , , Toshio Tatsuoka، نويسنده , , Yoshiko Horikawa، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
4
From page
763
To page
766
Abstract
7-(Hydroxyimino)cyclopropa[b]chromen-la-carboxylates (4a-c), highly potent antagonists for a phospholipase C-linked metabotropic glutamate receptor, mGluR1, were synthesized through cyclopropanation onto 4-oxo-4H-1-benzopyran-2-carboxylates (5a-c) utilizing dimethyloxosulfonium methylid followed by treatment with hydroxylamine.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
787995
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