Title of article
Novel imidazothioxanthones: Synthesis, DNA binding and cytotoxicity
Author/Authors
A. Varvaresou، نويسنده , , A. Tsotinis، نويسنده , , Th. Siatra-Papastaikoudi، نويسنده , , A. Papadaki-Valiraki، نويسنده , , D. E. Thurston، نويسنده , , T. C. Jenkins، نويسنده , , L. R. Kelland، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
6
From page
865
To page
870
Abstract
A new class of DNA-binding ligands (10a-f) has been synthesized and examined for DNA-binding affinity using thermal denaturation and for in vitro cytotoxicity in a number of cell lines. All the compounds were found to possess significant DNA-binding affinity which correlates with in vitro cytotoxicity across eight cell lines.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788018
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