Title of article
Benzopyran selective estrogen receptor modulators (SERMs): Pharmacological effects and structural correlation with raloxifene
Author/Authors
Timothy A. Grese، نويسنده , , James P. Sluka، نويسنده , , Henry U. Bryant، نويسنده , , Harlan W. Cole، نويسنده , , John R. Kim، نويسنده , , David E. Magee، نويسنده , , Ellen R. Rowley، نويسنده , , Masahiko Sato، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
6
From page
903
To page
908
Abstract
Several 2,3-diarylbenzopyrans have been evaluated in an ovariectomized rat model and found to exhibit tissue selective estrogen agonist activity on bone and serum lipid parameters. A structural model that accounts for the pharmacological similarity of these benzopyrans and the benzothiophene SERM, raloxifene, is proposed.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788027
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