Title of article
Conformationally restricted 1,5-diarylpyrazoles are selective COX-2 inhibitors
Author/Authors
Stephen R. Bertenshaw، نويسنده , , John J. Talley، نويسنده , , D.J. Rogier، نويسنده , , Matthew J. Graneto، نويسنده , , Carol M. Koboldt، نويسنده , , Yan Zhang، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
4
From page
2827
To page
2830
Abstract
Benzothiopyranopyrazoles and benzopyranopyrazoles containing either a sulfone or sulfonamide moiety were synthesized and tested for COX-1 and COX-2 inhibition. This new class of COX-2 selective inhibitors possess antiinflammatory activity in vivo.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1996
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788448
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