• Title of article

    Bifunctional antitumor agents: a DNA interactive enediyne from the pyrrolo[9,10-b]phenanthrene template

  • Author/Authors

    Graham B. Jones، نويسنده , , Jude E. Mathews، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1997
  • Pages
    4
  • From page
    745
  • To page
    748
  • Abstract
    Regioselective substitution of the intercalative pyrrolo[9,10-b]phenanthrene template was used to prepare an enediyne conjugate. The enediyne induced DNA strand scission at relevent concentration but proteolysis was not significant.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1997
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    788645