Title of article
Synthesis, characterization, interaction with DNA, and antitumor activity of a cis-Dichloroplatinum(II) complex linked to an intercalator via one methylene chain
Author/Authors
Yuji Mikata، نويسنده , , Kaoru Mogami، نويسنده , , Masako Kato، نويسنده , , Ichiro Okura، نويسنده , , Shigenobu Yano، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1997
Pages
4
From page
1083
To page
1086
Abstract
A cisplatin-type complex tethered to acridine intercalator via one methylene chain has been synthesized. Its structure was elucidated by X-ray crystallography. A permeability into cell, interaction with calf thymus DNA (ct-DNA), and antitumor activity against HeLa and P388 cells were studied.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1997
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788711
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