Title of article
Structure-activity studies of aryl-spaced decahydroisoquinoline-3-carboxylic acid ampa receptor antagonists
Author/Authors
Thomas J. Bleisch، نويسنده , , Paul L. Ornstein، نويسنده , , Nancy K. Allen، نويسنده , , Rebecca A. Wright، نويسنده , , David Lodge، نويسنده , , Darryle D. Schoepp، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1997
Pages
6
From page
1161
To page
1166
Abstract
We report the synthesis and structure activity studies of a series of decahydroisoquinoline AMPA antagonists where the distal acid is joined to the bicyclic ring nucleus with a spacer that contains an aromatic ring. These phenyl and thienyl substituted compounds are characterized as relatively potent AMPA antagoinsts.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1997
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788728
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