Title of article
SYNTHESIS OF ENANTIOMERICALLY PURE PHOSPHOROTHIOLATE ASSAY SUBSTRATE FOR PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C
Author/Authors
Cornelia Mihai، نويسنده , , Jan Mataka، نويسنده , , Suzette Riddle، نويسنده , , Ming-Daw Tsai، نويسنده , , Karol S. Bruzik، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1997
Pages
4
From page
1235
To page
1238
Abstract
An optimized synthesis of enantiopure (2R)-1,2-dioctanoyloxy- and (2R)-1,2-dipalmitoyloxypropane-thiophospho-(1D-myo-inositol) is reported starting from R-glycidol and the readily available 1D-1-tert-butyldiphenylsilyl-myo-inositol. The key synthesis of the phosphothiolester bond is carried out by the phosphoramidite chemistry. © 1997 Elsevier Science Ltd.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1997
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788743
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