Title of article
Inhibition of human cytomegalovirus protease by benzoxazinones and evidence of antiviral activity in cell culture
Author/Authors
Norman A. Abood، نويسنده , , Lori A Schretzman، نويسنده , , Daniel L. Flynn، نويسنده , , Kathrine A. Houseman، نويسنده , , Arthur J. Wittwer، نويسنده , , Vickie M. Dilworth، نويسنده , , Paul J. Hippenmeyer، نويسنده , , Barry C. Holwerda، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1997
Pages
4
From page
2105
To page
2108
Abstract
A series of 2-amino substituted benzoxazinones were prepared that potently inhibit human cytomegalovirus protease in vitro. Selected compounds demonstrate antiviral activity in cell culture, selectivity relative to chymotrypsin and elastase and stability with respect to hydrolysis in human plasma.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1997
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
788913
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