• Title of article

    Anti-histaminic activity of bromopyrrole alkaloids isolated from Caribbean Agelas sponges

  • Author/Authors

    Francesco Cafieri، نويسنده , , Rosa Carnuccio، نويسنده , , Ernesto Fattorusso، نويسنده , , Orazio Taglialatela-Scafati، نويسنده , , Teresa Vallefuoco، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1997
  • Pages
    6
  • From page
    2283
  • To page
    2288
  • Abstract
    Four Caribbean Agelas sponges (A. clathrodes, A. conifera, A. dispar, A. longissima) have been investigated for the alkaloid composition. Along with a series of known bromopyrrole alkaloids, two related novel compounds of this class, dispacamides C (7) and D (8), were found and their structures determined with spectroscopic methods. All the isolated Agelas bromopyrrole alkaloids have been evaluated for the antihistaminic activity on the guinea pig ileum.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1997
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    788948