• Title of article

    Sugar-substituted 2-azetidinones as cholesterol absorption inhibitors

  • Author/Authors

    Wayne D. Vaccaro، نويسنده , , Rosy Sher، نويسنده , , Harry R. Davis Jr.، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1998
  • Pages
    6
  • From page
    35
  • To page
    40
  • Abstract
    The asymmetric synthesis of a glucuronide conjugate of the 2-azetidinone cholesterol absorption inhibitor Sch 48461 was accomplished to confirm the structure of a metabolite isolated from in vivo sources. Key features of this article include the asymmetric synthesis of 2-azetidinones by Evanʹs chiral oxazolidinone methodology and glucuronide formation by a Mitsunobu protocol.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    1998
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    789174