Title of article
DNA gyrase inhibitory activity of ellagic acid derivatives
Author/Authors
Michele A. Weidner-Wells، نويسنده , , Jason Altom، نويسنده , , Jeffrey Fernandez، نويسنده , , Stephanie A. Fraga-Spano، نويسنده , , Jamese Hilliard، نويسنده , , Kwasi Ohemeng، نويسنده , , John F. Barrett، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
4
From page
97
To page
100
Abstract
Ellagic acid was found to inhibit E. coli DNA gyrase supercoiling with approximately the same potency as nalidixic acid. Tricyclic analogs of ellagic acid, which vary in the number and position of the hydroxy groups as well as their replacement with halogens, have been synthesized. The biological activity of these analogs is discussed.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789186
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