Title of article
Potent 3-spiropiperidine growth hormone secretagogues
Author/Authors
Lihu Yang، نويسنده , , Greg Morriello، نويسنده , , Kristine Prendergast، نويسنده , , Kang Cheng، نويسنده , , Tom Jacks، نويسنده , , Wanda W. -S Chan، نويسنده , , Klaus D. Schleim، نويسنده , , Roy G. Smith، نويسنده , , Arthur A. Patchett، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
6
From page
107
To page
112
Abstract
Systematic SAR studies of the different regioisomers and homologues of the spiro(indane-1,4′-piperidine) moiety in the growth hormone secretagogue L-162,752 are presented. Among them, spiro(3H-1-benzopyran-2,3′-piperidine) was found to afford secretagogues with low nanomolar in vitro activity.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789188
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