Title of article
Synthesis and immunosuppressive activity of ruthenium complexes
Author/Authors
Cecilia M. Bastos، نويسنده , , Kristin A. Gordon، نويسنده , , Timothy D. Ocain، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
4
From page
147
To page
150
Abstract
The syntheses and immunosuppressive activity of ruthenium complexes are described. One of the complexes (1a) was shown to be a potent inhibitor of human T-lymphocyte proliferation with an IC50 of 5 nM. The activity of these complexes compares favorably to the well known immunosuppressants Cyclosporin A and Rapamycin.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789196
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