Title of article
Synthesis of -enantiomers of 4′-thioarabinofuranosyl pyrimidine nucleosides
Author/Authors
Hiroshi Satoh، نويسنده , , Yuichi Yoshimura، نويسنده , , Shinji Sakata، نويسنده , , Shinji Miura، نويسنده , , Haruhiko Machida، نويسنده , , Akira Matsuda and Fuyuhiko Inagaki، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
4
From page
989
To page
992
Abstract
-Enantiomers of 4′-thioarabinofuranosyl pyrimidine nucleosides were synthesized from -xylose. Methyl 6 was converted to the corresponding xylitol 7, which was treated with MsCl and then Na2S to give 1,4-anhydro- -4-thioarabitol 8. As previously reported, Pummerer rearrangement of 8 followed by glycosylation with a silylated thymine and N4-acetylcytosine derivative and deprotection gave the corresponding α- and β- -4′-thioarabinofuranosyl pyrimidine nucleosides.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789362
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