Title of article
Anti-Helicobacter pylori agents. 2. Structure activity relationships in a new series of 2-alkylguanidino-4-furylthiazoles
Author/Authors
Yousuke Katsura، نويسنده , , Shigetaka Nishino، نويسنده , , Tetsuo Tomishi، نويسنده , , Kazuo Sakane، نويسنده , , Yoshimi Matsumoto، نويسنده , , Hirohumi Ishikawa، نويسنده , , Hisashi Takasugi، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
6
From page
1307
To page
1312
Abstract
SAR for antimicrobial activity against H. pylori was investigated in a new series of 2-alkylguanidino-4-furylthiazoles. Of the compounds obtained, cyclohexylmethyl and ethoxyethyl derivatives were identified as a novel class of anti-H. pylori agents which possessed potent and selective antimicrobial activity against H. pylori. These compounds also showed gastric antisecretory activity.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789424
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