Title of article
Practical synthesis of Taxol side chain
Author/Authors
Hyun-Joon Ha، نويسنده , , Gha-Seung Park، نويسنده , , Young-Gil Ahn، نويسنده , , Gwan Sun Lee، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
4
From page
1619
To page
1622
Abstract
Practical large scale synthesis of N-benzoyl-(2R,3S)-phenylisoserine methyl ester of the Taxol side chain has been attained from the coupling of chiral imine of N-[(S)-methylbenzyl]benzaldimine with (Z)-α-methoxy trimethylsilyl ketene acetal followed by the sequential reactions of lactamization, demethylation, methanolysis and N-benzoylation.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789483
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