Title of article
SAR studies of diaryltriazoles against bacterial two-component regulatory systems and their antibacterial activities
Author/Authors
Zhihua Sui، نويسنده , , Jihua Guan، نويسنده , , Dennis J. Hlasta، نويسنده , , Mark J. Macielag، نويسنده , , Barbara D. Foleno، نويسنده , , Raul M. Goldschmidt، نويسنده , , Michael J. Loeloff، نويسنده , , Glenda C. Webb، نويسنده , , John F. Barrett، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
6
From page
1929
To page
1934
Abstract
A series of diaryltriazole analogs was discovered to inhibit bacterial two-component regulatory systems in our primary assays, KinA/SpoOF and NRII/NRI. They also showed inhibitory activity in whole cell mechanism-based assays, and they possessed potent activities against several strains of Gram-positive pathogenic bacteria in the standard MIC broth assay.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789546
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