Title of article
Peptidyl chemosensors incorporating a fret mechanism for detection of Ni(II)
Author/Authors
Dierdre A. Pearce، نويسنده , , Grant K. Walkup، نويسنده , , Barbara Imperiali، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
6
From page
1963
To page
1968
Abstract
Hexapeptides incorporating two fluorophores flanking a tripeptide sequence that binds Ni(II) and Cu(II) with high affinity have been synthesized. While Cu(II) quenches the fluorescence of the resulting peptides, coordination of Ni(II) enables enhanced FRET (fluorescent resonance energy transfer) from one fluorophore to the other.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789552
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