Title of article
Actinomycin D, C2 and VII, inhibitors of Grb2-SHc interaction produced by Streptomyces
Author/Authors
Ji-Youn Nam، نويسنده , , Hyae-Kyeong Kim، نويسنده , , Kwang-Hee Son، نويسنده , , Sung-Uk Kim، نويسنده , , Byoung-Mog Kwon، نويسنده , , Mi Young Han، نويسنده , , Yong Je Chung، نويسنده , , Song-Hae Bok، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
2
From page
2001
To page
2002
Abstract
Actinomycin D, C2 and VII, cyclic peptides, inhibited Grb2 SH2 domain association (IC50 5–7 μM) with a phosphotyrosine containing peptide derived from the Shc protein (pTyr317). Actinomycins are the first examples of nonphosphorylated natural ligands of SH2 domain.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789559
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