Title of article
In situ generated O-Glycan core 1 structure as substrate for Gal(β1–3)GalNAc β-1,6-GlcNAc Transferase
Author/Authors
Gregor Dudziak، نويسنده , , Steffen Zeng، نويسنده , , Eric G. Berger، نويسنده , , Ricardo Gutiérrez Gallego، نويسنده , , Johannis P. Kamerling، نويسنده , , Udo Kragl، نويسنده , , Christian Wandrey، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
4
From page
2595
To page
2598
Abstract
β-Galactosidase from bovine testes was used in a one pot reaction together with a recombinant β-1,6-GlcNAc transferase for the synthesis of GlcNAc(β1–6)GalNAc(α1-OBn) (core 6-Bn). The galactosidase, which reversibly links galactose via a (β1–3) linkage to N-acetylgalactosamine, provides the substrate for the GlcNAc transferase in situ. The synthesis was carried out with a yield >90%.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789671
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