Title of article
Novel protein kinase C inhibitors: α-terthiophene derivatives
Author/Authors
Darrick S. H. L. Kim، نويسنده , , Curtis L. Ashendel، نويسنده , , Qin Zhou، نويسنده , , Ching-Te Chang، نويسنده , , Eung Seok Lee، نويسنده , , Ching-jer Chang، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
4
From page
2695
To page
2698
Abstract
A series of α-terthiophene derivatives were prepared and their protein kinase C inhibitory activity were evaluated. The aldehyde derivatives were most potent inhibitors (IC50< 1 μM). α-Terthiophene monoaldehyde was inactive in the inhibitions of protein kinase A, mitogen activated protein kinase and protein tyrosine kinase.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789689
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