Title of article
Antiinflammatory 4,5-diarylimidazoles as selective cyclooxygenase inhibitors
Author/Authors
Thomas E. Barta، نويسنده , , Michael A. Stealey، نويسنده , , Paul W. Collins، نويسنده , , Richard M. Weier، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
6
From page
3443
To page
3448
Abstract
The synthesis and activity of a series of 4,5-diarylimidazole analogs are described. One analog had an IC50 of 80 nM, was 6750-selective against COX-1, and demonstrated in vivo potency in the mouse air pouch model
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1998
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789834
Link To Document