Title of article
Highly constrained dipeptoid analogues containing a type II′ β-turn mimic as novel and selective CCK-A receptor ligands
Author/Authors
Natalia de la Figuera، نويسنده , , Mercedes Mart?n-Mart?nez، نويسنده , , Rosario Herranz، نويسنده , , M. Teresa Garc?a-L?pez، نويسنده , , Miriam Latorre، نويسنده , , Edurne Cenarruzabeitia، نويسنده , , Joaqu?n del R?o، نويسنده , , Rosario Gonz?lez-Mu?iz، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
6
From page
43
To page
48
Abstract
Conformationally constrained dipeptoid analogues containing the type II′ β-turn mimic (2S,5S,11bR)-2-amino-3-oxohexahydroindolizino[8,7-b]indole-5-carboxylate framework in place of the α-MeTrp residue, show high binding affinity and selectivity for CCK-A receptors, suggesting that a turn-like conformation could contribute to the bioactive conformation at this CCK receptor subtype.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789890
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