Title of article
In vitro susceptibility of Helicobacter pylori to trifluoromethyl ketones
Author/Authors
Masami Kawase، نويسنده , , Hiromi Harada، نويسنده , , Setsuo Saito، نويسنده , , Jiongmo Cui، نويسنده , , Satoru Tani، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
2
From page
193
To page
194
Abstract
Heteroaromatic trifluoromethyl ketones (TFMKʹs) showed strong inhibitory activity against Helicobacter pylori. The MIC50 observed for 2-trifluoroacetonylbenzoxazole (1) is 20-fold more active than metronidazole and is only twice as high as that of clarithromycin. The inhibitory mode of TFMKʹs on Hp growth was not related to inhibition of urease.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
789919
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