Title of article
Nucleomimetic strategy for the inhibition of HIV-1 nucleocapsid protein NCp7 activities
Author/Authors
Sabine Druillennec، نويسنده , , Hervé Meudal، نويسنده , , Bernard P. Roques، نويسنده , , Marie-Claude Fournie-Zaluski، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
6
From page
627
To page
632
Abstract
We report the synthesis and biological properties of three modified dinucleotides T*G, G*T and T*T in which the natural phosphodiester linkage has been replaced by a methylene carboxamide unit. They have been designed to act as nucleomimetics of a sequence recognized by the HIV-1 nucleocapsid protein NCp7 and to inhibit this interaction.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790007
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