Title of article
Ring constrained analogues of the orvinols: The furanomorphides
Author/Authors
Stephen M. Husbands، نويسنده , , Simon W. Breeden، نويسنده , , Konstantinos Grivas، نويسنده , , John W. Lewis، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
4
From page
831
To page
834
Abstract
A series of furanomorphides were synthesised as ring-constrained analogues of buprenorphine and related orvinols. Evaluation in binding and functional assays has shown that the furanomorphides have reduced efficacy at the μ opioid receptor compared to the orvinols.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790046
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