Title of article
Formation of glucoraphanin by chemoselective oxidation of natural glucoerucin: A chemoenzymatic route to sulforaphane
Author/Authors
R. Iori and T. Cembali، نويسنده , , R. Bernardi ، نويسنده , , D. Gueyrard، نويسنده , , P. Rollin، نويسنده , , S. Palmieri، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
2
From page
1047
To page
1048
Abstract
A new semi-synthetic way to produce glucoraphanin (2), the bio-precursor of the potential anticarcinogen sulforaphane (3), has been developed. Starting from glucoerucin (1), isolated from ripe seeds of Eruca sativa, glucoraphanin was obtained through chemoselective oxidation. Controlled myrosinase-catalysed hydrolysis of this precursor quantitatively afforded sulforaphane.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790088
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