Title of article
Thiazolo[4,5-d]pyrimidine thiones and -ones as corticotropin-releasing hormone (CRH-R1) receptor antagonists
Author/Authors
James P. Beck، نويسنده , , Matt A. Curry، نويسنده , , Robert J. Chorvat، نويسنده , , Larry W. Fitzgerald، نويسنده , , Paul J. Gilligan، نويسنده , , Robert Zaczek، نويسنده , , George L. Trainor، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
4
From page
1185
To page
1188
Abstract
A series of thiazolo[4,5-d]pyrimidine thiones and -ones was prepared and discovered to have good binding affinity to the CRH-R1 receptor, thus showing promise as a new class of potential anxiolytics and/or antidepressants.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
1999
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
790116
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